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KMID : 0616619970030010095
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Journal of Soonchunhyang Medical College
1997 Volume.3 No. 1 p.95 ~ p.102
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P53 protein expression in malignant melanoma and benign melanocytic nevi
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Abstract
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This study was carried out to evaluate the aberrant expression of ?? protein using immunohistochemical method in 10 malignant melanoma and 10 melanocytic nevi. Eight out of 10(80%) and two out of 10(20%) showed positive reaction in the nucleus of malignant melanoma and benign melanocytic nevi, respectively.
In conclusion, the demonstration of ?? protein in benign melanocytic nevi greatly hinders the possibility of a diagnostic use of ?? immunostaining in differentiating malignant melanoma from benign melanocytic nevi.
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KEYWORD
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